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Wrapping Up Multiple Sclerosis

With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn’t stand a chance.

Dr. Stephen Hauser, examining a patient, gestures for her to look straight ahead.

Illuminating Depression’s Circuitry

If depression is caused by flawed brain circuitry, it may be possible to shift that circuitry toward healthy neural processing instead. UCSF researchers hope to map and correct aberrant neural behavior to cure mood disorders.

Illustration of the silhouette of a person’s head; behind the person is a beautiful blue sky with fluffy clouds; inside the head is a swirling galaxy, with a hand reaching in.

Science Interrupted

These days, young investigators spend half their time applying for grants to keep their labs afloat. The competition is so fierce that the next generation of academic scientists is at risk and, by extension, so is science itself.

Illustration of science beakers and a female scientist looking stressed.

My Lab: Dissected

Two major factors determine whether you get cancer – your genes and what you have been exposed to in the environment, says Allan Balmain, PhD, co-leader of UCSF’s Cancer Genetics Program.

Allan Balmain talks to a research assistant in his lab.

Culturing For Cures

There are 100 trillion bacterial cells living in and on our bodies. In the spring issue of UCSF Magazine, find out how these bacteria could be the key to treating and preventing a number of conditions from asthma to obesity.

Illustration of a human made out of microbiome bacterial cells with bacteria floating all around them.

The Gene Machine

Precision Medicine Pillar No. 5: Omics Medicine. Molecular biologist Nevan Krogan's work is not only illuminating how genes and proteins function, it's also shedding light on the underlying biology of disease for each person.

Illustration of intertwining circles with silhouettes of a diverse groups of people along the circles with a constellation of connected dots in the middle.

A Digital Path to Health

Precision Medicine Pillar No. 6: Digital Health. The Center for Digital Health Innovation shepherds the development of digital health innovations created at UCSF and validates the effectiveness of devices from both inside and outside the institution.

Illustration of intertwining circles with silhouettes of a diverse groups of people on one circle.

The Fabric of Disease

Precision Medicine Pillar No. 4: Computational Health Sciences. Computationally intensive approaches are used to analyze and cross-analyze large but discrete collections of data, such as patient health histories and genetic makeup.

Illustration of silhouettes of a diverse groups of people in a line.

Big Data, Tailored Care

Precision Medicine Pillar No. 3: Clinical Discovery. Researchers are taking vast amounts of patient data, often collected through first-ever clinical studies, and putting it into tools like MS Bioscreen that have a direct impact on patient care.

Illustration of intertwining circles with silhouettes of a diverse groups of people along the circles; one person is highlighted in orange.

Digging Deeper Into Cancer

Precision Medicine Pillar No. 2: Basic Discovery. The long path to developing potent new treatments often starts with an observation in the lab that then leads to a question about a fundamental life process.

Illustration of silhouettes of a diverse groups of people.

It’s All About Networking

Precision Medicine Pillar No. 1: Knowledge Network. With an increased ability to harvest information automatically and more powerfully, scientists can find the connections among discoveries that would otherwise go unrecognized.

Illustration of intertwining circles with silhouettes of a diverse groups of people along the circles.