‘Undruggable’ Cancers Slowed by Targeting Growth Signals
Researchers have identified a new strategy for potentially treating a subset of intractable cancers by decoupling the entire RAS / MAP Kinase signaling pathway from external growth signals.
University of California San Francisco
Give to UCSFResearchers have identified a new strategy for potentially treating a subset of intractable cancers by decoupling the entire RAS / MAP Kinase signaling pathway from external growth signals.
A collaboration between three labs at UCSF has resulted in an unprecedented look at a member of a vital and ubiquitous class of proteins called integrins.
A comprehensive genetic analysis of metastatic prostate cancer has, for the first time, revealed a number of major ways in which abnormal alterations of the genome propel this aggressive form of the disease.
In an achievement that has significant implications for research, medicine, and industry, UCSF scientists have genetically reprogrammed human immune cells without using viruses to insert DNA
UCSF and a newly formed, next-generation nonprofit organization, Health Hub, are announcing their plans to affiliate.
UCSF researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs – checkpoint inhibitors.
Silicon Valley is helping researchers like Wendell Lim move basic science breakthroughs into translational applications, making treatments available to patients faster than normally possible.
The journey from discovering and developing effective, precise medications to using them correctly and safely in patients is hardly fast and easy. Nor is it a straight shot. Scientists in the UCSF School of Pharmacy are challenging the status quo every step of the way.
Researchers have demonstrated the ability to program groups of individual cells to self-organize into multi-layered structures reminiscent of simple organisms or the first stages of embryonic development.
Smoking cessation intervention for young adults conducted on Facebook found smokers are 2.5 times more likely to quit with the Facebook-based treatment than if they were referred to an online program.
UCSF neuroscientist identified the first potential treatment for the brain damage caused by exposure to cosmic rays.
UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer.
Automated breast-density evaluation was just as accurate in predicting women’s risk of breast cancer, found and not found by mammography, as subjective evaluation done by radiologists.
In the absence of rigorous preclinical testing from the FDA, health systems should carefully scrutinize digital tools that interact with electronic health records to recommend patient diagnoses or therapies.
A type of AI known as advanced machine learning can classify essential views from heart ultrasound tests faster, more accurately and with less data than board-certified echocardiographers.