Recent articles by Laura Lane

HIV gene causes formation of nuclear herniations halting cell division, Gladstone researchers find

November 01, 2001
Researchers at the Gladstone Institute of Virology and Immunology have found that an HIV gene called Vpr causes the membrane surrounding the nucleus-the nuclear envelope-to form herniations that project and retract much like solar flares radiating from the surface of the sun.

HIV infects subset of T cells leading to depletion, Gladstone researchers find

October 16, 2001
Researchers at the Gladstone Institute of Virology and Immunology and co-authors have found that naive T cells, are susceptible to the bullets of HIV infection even before they step onto the battlefield.

Inhibitory switch found for master regulator of inflammation, Gladstone reseachers report

August 30, 2001
Researchers at the Gladstone Institute of Virology and Immunology have now discovered a new pathway by which the cell regulates the activity of NF-kB, setting the stage for new therapeutic approaches.

Gladstone researchers find clue to Alzheimer's disease risk factor

July 16, 2001
For years, scientists have recognized that a protein called apoE4 is a major risk factor for developing Alzheimer's disease.

Gladstone researchers discover possible Achilles Heel in infection by lethal Ebola and Marburg virus

July 12, 2001
The folate receptor, a protein expressed on the surface of many human cells, could be capable of transporting much more into the cell than just folic acid - the B vitamin involved in normal bodily functions and cell development.

Genes crucial in the control of Tuberculosis found by Gladstone researchers

July 02, 2001
Controlling a tuberculosis infection requires an interplay of a distinct set of genes and immune system cells. Researchers at the Gladstone Institute of Cardiovascular Disease are showing for the first time that the absence of one of those genes, called CCR2, can have fatal consequences.

Chemokine receptor gene crucial in the control of Tuberculosis, Gladstone/UCSF researchers find

July 02, 2001
Researchers are showing for the first time that the absence of the gene for CCR2, a receptor on white blood cells known to be important for cell migration, can have fatal consequences.

Drug resistant HIV allows body to continue producing virus-fighting cells, Glastone finds

May 30, 2001
HIV that has become resistant to powerful drugs called protease inhibitors may not be a dire sign of decline after all, researchers from the Gladstone Institute of Virology and Immunology have shown.

Molecule reduces Alzheimer plaques in brain, researchers report

April 30, 2001
The highways and byways through which the brain exchanges messages require maintenance much as any municipal road. What would happen if such debris were left to accumulate? Alzheimer's disease would result.

The HIV NEF protein plays both offense and defense in the battle between the AIDS virus and the body

April 11, 2001
In fighting the body's immune system, HIV owes part of its success to its ability to destroy those cells normally recruited to mount the body's counter-attack against the HIV-infected cells...