Recent articles by Anne Holden

Genome Editing Goes Hi-Fi

February 10, 2014
Scientists at the UCSF-affiliated Gladstone Institutes have found a way to efficiently edit the human genome one letter at a time, paving the way for therapies that cure disease.

Robert Mahley Receives Wellcome Trust Funds to Combat Alzheimer’s Disease

December 11, 2013
Renowned Alzheimer’s researcher and founding president of the UCSF-affiliated Gladstone Institutes, Robert Mahley, MD, PhD, has received a Seeding Drug Discovery Award from the Wellcome Trust.

Fast-Mutating DNA Sequences Shape Early Development; Guided Evolution of Uniquely Human Traits

November 11, 2013
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.

Gladstone Scientist to Receive Prestigious Pacesetter Award

October 22, 2013
Lennart Mucke, MD, who directs neurological research at the Gladstone Institutes, next week will receive the ARCS Foundation’s 2013 Pacesetter Award.

Gladstone Scientists Win $12.5M in Prestigious Grant Awards

September 30, 2013
Three Gladstone scientists have won research awards from divisions of the National Institutes of Health equaling an approximate total of $12.5 million over five years for their groundbreaking research to overcome HIV/AIDS.

Scientists Devise Innovative Method to Profile and Predict the Behavior of Proteins

August 08, 2013
A team of investigators led by UCSF and the Gladstone Institutes has found a way to map an enzyme’s underlying molecular machinery, revealing patterns that could allow them to predict how an enzyme behaves – and what happens when this process disrupted.

Scientists Identify Molecular Switch that Kick-Starts Formation of Arteries

July 03, 2013
The ability to form blood vessels is one of evolution’s crowning achievements. Now, scientists at the Gladstone Institutes have identified the molecular signals that direct the process of committing endothelial cells to become arteries or veins during embryonic development.

High-Resolution Mapping Technique Uncovers Underlying Circuit Architecture of the Brain

June 27, 2013
Using an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.

Scientists Discover DNA Damage Occurs as Part of Normal Brain Activity

April 01, 2013
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process.

Scientists Identify Infection Strategy of Widespread Virus

December 20, 2012
Scientists at the Gladstone Institutes have mapped the molecular mechanism by which a virus known as cytomegalovirus (CMV) so successfully infects its hosts. This discovery paves the way for new research avenues aimed at fighting this and other seemingly benign viruses that can turn deadly.