These results confirm that the HPV virus causes head and neck cancer by inactivating the same proteins that are mutated in smoking-induced cancer.
Researchers at UCSF and the Gladstone Institutes have received an $18 million grant from the National Institutes of Health to launch the Psychiatric Cell Map Initiative.
Researchers identified a protein that cancer cells use as a shield to protect the PI3K pathway against targeted drugs, and showed that blocking this protein allowed previously ineffective therapies to slow cancer cell growth and shrink tumors.
New study could make it much easier for physicians to use the genetic profile of a patient’s tumor to pick the chemotherapy treatment with the fewest side effects and best chance of success.
A research team led by scientists at UCSF has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs.
In a major advance for fundamental biological research, UCSF scientists have developed a tool capable of illuminating previously inscrutable cellular signaling networks.
Researchers at UCSF and elsewhere are turning to virtual experiments for the initial steps of drug development.
UCSF researchers have used data-mining computational tools to identify a treatment for hepatocellular carcinoma, a cancer associated with underlying liver disease and cirrhosis that often only becomes symptomatic when it is very advanced.
A $22 million investment via California State Assembly Bill 2664 is supporting innovation and entrepreneurship at UC San Francisco and across the University of California system.
Steven Altschuler and Lani Wu are using artificial intelligence to spot and label potential medical uses for biological compounds.