UCSF scientists have figured out why some lung cancers become drug-resistant after initially responding to targeted therapies.
UCSF researchers have devised a CRISPR-based system called SLICE, which will allow scientists to rapidly assess the function of each and every gene in “primary” immune cells.
Genetics may predispose some people to both Alzheimer’s disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease.
To develop novel therapies to treat specific subtypes of COPD, and potentially even to reverse some of the symptoms, scientists at UCSF are taking a precision medicine approach to the disease.
Almost half of the nearly 10 million patients with active tuberculosis each year could potentially be cured with significantly shorter treatments than current guidelines recommend.
The ascendancy of CRISPR systems raises a grand hope: If these tools can illuminate the causes of disease in the laboratory, why not bring them into the clinic to treat patients?
A new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of treatment even before changes are identified on scans.
Scientists at UCSF have assembled a searchable database of normal human immunity that researchers can now use as an instant comparison group in studies of the immune system and immune dysfunction.
Nearly all studies of telomere genetics have been performed in adult populations of European or Asian ancestry, meaning that studies aiming to understand how early environmental exposures impact telomere length across different ethnic groups can’t easily assess the role of natural variations in telomere biology.