A new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of treatment even before changes are identified on scans.
Scientists at UCSF have assembled a searchable database of normal human immunity that researchers can now use as an instant comparison group in studies of the immune system and immune dysfunction.
Nearly all studies of telomere genetics have been performed in adult populations of European or Asian ancestry, meaning that studies aiming to understand how early environmental exposures impact telomere length across different ethnic groups can’t easily assess the role of natural variations in telomere biology.
UCSF researchers have discovered how a mutation in a gene regulator called the TERT promoter confers “immortality” on tumor cells, enabling the unchecked cell division that powers their aggressive growth.
By creating a tailored drug cocktail that matches the mutations of a brain tumor, a new precision medicine approach may move the needle for children with high-grade gliomas.
Health professionals should recommend against parents using direct-to-consumer genetic sequencing to diagnose or screen their newborns.
Researchers have identified a new strategy for potentially treating a subset of intractable cancers by decoupling the entire RAS / MAP Kinase signaling pathway from external growth signals.
A new UC San Francisco study has discovered a key biological difference in how people of European and Chinese descent put on weight — a finding that could help explain why Asians often develop type 2 diabetes at a much lower body weight than Caucasians.