In a new study discovered that variants at a single site on Chromosome 6 are associated with a significantly higher risk of developing erectile dysfunction.
Nearly all studies of telomere genetics have been performed in adult populations of European or Asian ancestry, meaning that studies aiming to understand how early environmental exposures impact telomere length across different ethnic groups can’t easily assess the role of natural variations in telomere biology.
In DNA sequencing study of TD, UCSF researchers and their collaborators have unearthed new data suggesting a potential role for disruptions in cell polarity in the development of this condition.
UCSF researchers have uncovered 12 new anti-CRISPR genes, some of which can inhibit different CRISPR types and could be critical to future gene-editing therapies.
Genetic mutations in a form of non–small cell lung cancer may drive tumor formation by blurring cells’ perception of key growth signals, according to a new laboratory study published Aug. 31, 2018, in Science.
In these patients, chronic tissue inflammation causes an over-active protein to introduce mutations across the genome, some of which eventually lead to cancer.
Researchers have identified a new strategy for potentially treating a subset of intractable cancers by decoupling the entire RAS / MAP Kinase signaling pathway from external growth signals.
A decades-old medical mystery has been solved by researchers at UCSF and St. Jude Children’s Research Hospital in Tennessee, who have discovered a pair of inherited genetic mutations underlying a familial blood disorder that sometimes leads to leukemia.