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By studying fossilized teeth from thousands of extinct rodent species, UCSF and University of Helsinki scientists have shown how fundamental evolutionary mechanisms drive the emergence of novel mammalian stem cells.
A newly discovered cache of industry documents reveals that the sugar industry worked closely with the National Institutes of Health in the 1960s and ‘70s to develop a federal research program focused on approaches other than sugar reduction to prevent tooth decay in American children.
Drugs made from naturally occurring molecules found in fish oil could help thousands of Americans whose coronary and leg arteries renarrow after surgery.
UCSF pathologist Charles Chiu answers some key questions about why the Ebola outbreak has spread so far, how it might be contained and what the real dangers are for people in the U.S.
A newly discovered population of immune cells in tumors is associated with less severe cancer outcomes in humans, and may have therapeutic potential, according to a new UCSF study.
A UCSF physician who treats birth defects affecting the face has teamed up with a European expert on animal evolution to create rodent teeth that harken back in evolutionary time.
Researchers at UCSF have found that children with sensory processing disorders have decreased structural brain connections in specific sensory regions different than those in autism, further establishing SPD as a clinically important neurodevelopmental disorder.
A new technology uses near-infrared light to better detect cavities without the radiation of X-rays. It's one of several innovations that could soon change your dental chair experience.
Researchers are recording brain activity in visually stunning ways that could lead to targeted therapies for Alzheimer’s, autism and other diseases.
UCSF neuroscientist Adam Gazzaley, MD, PhD, is hoping to paint a fuller picture of what is happening in the minds and bodies of those suffering from brain disease with his new lab, Neuroscape, which bridges the worlds of neuroscience and high-tech.
Teams of scientists at UCSF are collaborating to build upon existing imaging techniques and find new ways to monitor diseases using creative applications of emerging technologies.
Scientific progress and innovation are speeding along, faster than ever before, but arbitrary spending cuts are posing an unprecedented threat.
Sally Rockey, deputy director for Extramural Research at the National Institutes of Health, is giving a talk titled “NIH: Interesting Times, Challenging Times” at UCSF on Tuesday, Sept. 24.
A team of investigators led by UCSF and the Gladstone Institutes has found a way to map an enzyme’s underlying molecular machinery, revealing patterns that could allow them to predict how an enzyme behaves – and what happens when this process disrupted.
Stem-cell researchers at UCSF have found a key role for a protein called BMI1 that may help scientists direct the development of tissues to replace damaged organs in the human body.
Sensory processing disorders are more prevalent in children than autism. In a groundbreaking new study, UCSF researchers have for the first time shown a biological basis for the disease in the brain structure.
Using an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.
Hospital MRIs may be better at predicting long-term outcomes for people with mild traumatic brain injuries than CT scans, according to a clinical trial led by researchers at UCSF and the San Francisco General Hospital and Trauma Center.
<p>Rebecca Smith-Bindman, MD, a professor of radiology and biomedical imaging at UCSF, answered these questions in light of a new study that shows that medical imaging is increasing even in health maintenance organization systems (HMOs), which don’t have a financial incentive to conduct them.</p>
<p>Medical geneticist Ophir Klein's studies of stem cells in tooth development and of stem cell changes in the gut may lead to new strategies for regenerating teeth and for treating craniofacial abnormalities.</p>
<p>By understanding the underlying biological processes that allow teeth to continuously grow in rodents and other mammals, Klein’s research aims to apply those principles to regenerative medicine in humans. Klein predicts that one day patients will be able to replace their own lost teeth with living, biological replicas instead of the prosthetics oral surgeons implant today.</p>
<p>Having developed an algorithm that discovered a large quantity of drug-producing bacteria in and on humans, Fischbach has turned his lab’s attention to studying their populations and interactions with each other. This, he posits, can greatly influence a person’s overall health and disease.</p>
<p>Swallowing pills means medication must face the challenge of surviving the harsh environment of the digestive tract. As a result, people must take larger doses than they need. Using micro and nano-fabrication techniques developed by the computer chip industry, Desai’s lab is creating tiny devices that take multiple drugs directly to where they are needed, using less medication, minimizing side effects and making the process safer for the patient. </p>
Sanofi-Aventis and UCSF have formed two research and development collaborations that join together leaders from academia and industry to more rapidly advance groundbreaking innovation from the lab to the patient.
Susan Hyde, an award-winning professor and scientist with the UCSF School of Dentistry, promotes practices that preserve oral health and quality of life for both patients and practitioners.
In a recent UCSF-led study in mice, researchers developed a method to stabilize living lung tissue for imaging without disrupting the normal function of the organ. The method allowed the team to observe, for the first time, both the live interaction of living cells in the context of their environment and the unfolding of events in the immune response to lung injury.
Brain cancers are deadly more often than not, but UCSF researchers have determined that a particular genetic signature in is associated with longer survival, a discovery that may lead to better therapies for some of the deadliest brain cancers.
Weight gain and environmental pollutants might be linked, an award-winning worm researcher suggests.
A team of UCSF researchers has engineered E. coli with the key molecular circuitry that will enable genetic engineers to program cells to communicate and perform computations.
Ophir Klein wants to use stem cells to grow teeth. Because teeth are simple in comparison to large, vital organs, they may serve as a proving ground for regenerative medicine.