Gene Therapy Is Halting Cancer. Can It Work Against Brain Tumors?
New CAR-T gene therapy techniques could extend survival for patients with glioblastoma.
University of California San Francisco
Give to UCSFNew CAR-T gene therapy techniques could extend survival for patients with glioblastoma.
UCSF scientists have been awarded more than $30 million to develop “tissue GPS,” a new system using engineered T cells to guide therapies directly to their targets in the brain to treat neurological diseases like cancer, multiple sclerosis and Alzheimer’s.
An upcoming Supreme Court ruling could put a stop to telehealth abortion services nationally, and limit access to mifepristone, one of two drugs commonly used in abortion care.
A first of its kind study finds that the COVID vaccine is safe to administer during pregnancy, causing no abnormal delays when the infants were tested at 12 months and again at 18 months.
Researchers recently identified a universal, essential biomarker for the childhood cancer neuroblastoma – and the biomarker could be a potential new target for treatment. Neuroblastoma accounts for
A new drug candidate permanently modifies a wily cancer-causing mutation, paving the way for making pancreatic cancer treatable, or perhaps even curable.
Delivering medicine through amniotic fluid is as effective as delivering it to the fetal brain via cerebrospinal fluid to treat serious disordrs such as Angelman syndrome.
Juvenile myelomonocytic leukemia (JMML) is a rare but aggressive childhood leukemia. While hematopoietic stem cell transplantation is curative for some patients, approximately half of all patients see
Daily cannabis smokers have a 25% increased risk of heart attack and a 42% increased risk of stroke compared to non-users.
Tracey Woodruff, PhD, MPH, offers insights on what her research on microplastics has led her to change how she and her family eats and what cleaning products she uses.
UCSF scientists found a way to predict Alzheimer’s disease up to seven years before symptoms appear by analyzing patient records with machine learning. Conditions that most influenced prediction of Alzheimer’s were high cholesterol and, for women, osteoporosis.
Medication abortion can be delivered safely and effectively through telemedicine, according to new research that comes as the U.S. Supreme Court is about to hear a case that could severely restrict access to one of the two pills that are used to induce abortions.
Cancer immunotherapy is hindered by the fact that engineered immune cells often get worn out and depleted before they've killed a tumor. A UCSF team has identified mutations that give cancerous lymphoma T-cells their superpower and transfer those genes into engineered, therapeutic immune cells.
In a first, scientists at UCSF and Stanford identified genetic variants that predict whether a patient is likely to respond to treatment for preterm birth. Screening for mutations could allow doctors to target medications to those most likely to benefit. No medication is currently available in the U.S. to treat preterm birth.
Combining testosterone-blocking drugs in patients with prostate cancer relapse prevents the spread of cancer better than treatment with a single drug.
Young Black and Hispanic women with multiple sclerosis fare worse than young white women with the disease. Minority women were more likely to have more advanced disease and faced greater challenges in pregnancy.
Fruit bats have a genetic system that controls blood sugar without fail. Learning from that system can help us make better insulin- or sugar-sensing therapies for human patients.
UC San Francisco’s Thomas G. Martin, MD, a leading expert in blood cancers, has received a grant of nearly $4.6 million from the California Institute of Regenerative Medicine (CIRM) to produce a CAR T
Cell biologist and engineer Matthew Kutys, PhD, and his team harness organoids – living tissues derived from patient tumors – to study how cancer spreads.
UCSF’s industry archives expose the marketing tactics that fueled the opioid epidemic.
Eric J. Small, MD, UCSF professor of Medicine and Urology Credit: UCSFThe American Society of Clinical Oncology (ASCO) has elected Eric J. Small, MD, FASCO, to serve as its president for the term
Researchers at UCSF and UC Berkeley are investigating the impact of pre- and post-natal exposures to tobacco smoke on the survival rate of children with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
Hematologists and oncologists from around the world will present new research and clinical findings at the American Society of Hematology’s (ASH) 65th Annual Meeting and Exposition. This year’s meeting will be held in San Diego from Dec. 8-12, 2023.
Thirty-two UCSF scientists are among the most influential individuals in their respective fields, according to the most recent analysis of research citations by the science and intellectual property company, Clarivate.
UCSF researchers found that regular screening is not always sufficient to prevent an advanced breast cancer diagnosis.