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A new study by UCSF researchers revealed the intriguing possibility that HP1α binds to stretches of DNA and pulls it into droplets that shield the genetic material inside from the molecular machinery of the nucleus that reads and translates the genome.
UCSF researchers have drawn a link between genetic abnormalities in neurodegenerative diseases and the formation of RNA foci, work the scientists said may open avenues to the development of new drug treatments.
UCSF researchers have used data-mining computational tools to identify a treatment for hepatocellular carcinoma, a cancer associated with underlying liver disease and cirrhosis that often only becomes symptomatic when it is very advanced.
A newly approved drug that is the first to reflect the current scientific understanding of multiple sclerosis is holding new hope for the hundreds of thousands Americans living with the disease. It also highlights the importance of clinician scientists like UCSF’s Stephen Hauser who are working to transform research into cures for patients.
Researchers at UCSF have developed a new optogenetic tool that can be used to completely eliminate single cells from brain networks in animals. The researchers believe the new tool will enable exquisitely precise experiments to help researchers understand how each cell contributes to the whole.
In findings that show the effectiveness of a new strategy for treating multiple sclerosis, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab in both relapsing multiple sclerosis and primary progressive multiple sclerosis.
White blood cells called neutrophils race after bacteria at speeds up to a thousand times that of most human cells by moving in a special way. Lillian Fritz-Laylin and Megan Riel-Mehan want to know how that works.
Graduate student Lauren Rodda captured a microscopic mage of a mouse gut, which highlights her work to understand the germinal center, where immune cells compete to be the best at recognizing an invading pathogen.