Alzheimer ‘Tau’ Protein Far Surpasses Amyloid in Predicting Toll on Brain Tissue
Brain imaging of pathological tau-protein reliably predicts the location of future brain atrophy in Alzheimer’s patients a year or more in advance.
University of California San Francisco
Give to UCSFBrain imaging of pathological tau-protein reliably predicts the location of future brain atrophy in Alzheimer’s patients a year or more in advance.
With the rise of “direct-to-consumer” DNA tests, investigating your genes is easier than ever. But taking one of these tests may not be right for you, says UCSF professor Kathryn Phillips, PhD, who studies new health care technologies.
UCSF physician Peter Ganz and colleagues at Colorado-based SomaLogic Inc., are developing what they call “liquid health check” technology – a single blood test capable of painting a detailed portrait of a person’s current health and future disease risks.
Using standard animal model of Down syndrome, scientists were able to correct the learning and memory deficits associated with the condition with drugs that target the body’s response to cellular stresses.
Adam L. Boxer answers questions about the potential of "basket trials" to accelerate drug development for dementia and neurodegenerative disease.
Cystic Fibrosis (CF) in Puerto Rico and the Dominican Republic is dominated by unusual gene mutations not often observed in previously studied CF populations. Majority of Dominican patients had no detectable mutations at all in the gene that is thought to drive 95 percent of CF cases.
The cause of the pancreatic inflammation plaguing a rural California family has been a medical mystery since it was first described 51 years ago. Now genetic sleuth-work by researchers from UC San Francisco and the University of Chicago has solved the mystery: pointing to a novel gene mutation as the cause of the family’s inherited pancreatitis.
Now in its sixth year, the Best Global Universities rankings focus on schools’ academic research and reputation.
The UCSF scientists who identified the two known human genes that promote “natural short sleep” have now discovered a third, and it’s also the first gene that’s ever been shown to prevent the memory deficits that normally accompany sleep deprivation.
UCSF study conducted in songbirds shows that what at first appear to be genetic constraints on birds’ song learning abilities could be largely eliminated by tailoring instruction to better match the birds’ inborn predispositions.
A new genetic test found that Quincy's aggressive blood cancer had an unusual mutation on the FLT3 gene. That gave Quincy’s doctors a life-saving idea.
UCSF Benioff Children’s Hospitals have successfully treated a months-old infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer.
UCSF scientists who identified the only human gene known to promote “natural short sleep” have discovered a second.
Study shows that the adult-to-iPSC conversion process can mutate DNA found in mitochondria, causing mice and humans to reject iPSCs, and stem cell transplants more generally.
In a paper researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity of genes in human neurons generated from stem cells, the first successful merger of stem cell-derived cell types and CRISPR screening technologies.
Advanced sleep phase that lures people to sleep at 8 p.m., enabling them to wake up as early as 4 a.m — previously believed to be very rare — may affect at least one in 300 adults.
A study of newborn infants has identified a compound produced by gut bacteria that appears to predispose certain infants to allergies and asthma later in life.
Brain damage associated with MS specifically targets a common class of brain cells called projection neurons