New Clues on Stem Cell Transplant Rejection Revealed in Study
Study shows that the adult-to-iPSC conversion process can mutate DNA found in mitochondria, causing mice and humans to reject iPSCs, and stem cell transplants more generally.
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Tweaked CRISPR in Neurons Gives Scientists New Power to Probe Brain Diseases
In a paper researchers describe a technique that uses a special version of CRISPR developed at UCSF to systematically alter the activity of genes in human neurons generated from stem cells, the first successful merger of stem cell-derived cell types and CRISPR screening technologies.
‘Limitless Potential’ of Artificial Protein Ushers in New Era of ‘Smart’ Cell Therapies
Researchers devised “smart” cells that behave like tiny autonomous robots which may be used to detect damage and disease, and deliver help at just the right time and in just the right amount.
Frog Protein May Mitigate Dangers Posed by Toxic Marine Microbes Fueled by Climate Change
A new study from UCSF suggests that a protein found in the common bullfrog may one day be used to detect and neutralize a poisonous compound produced by red tides and other harmful algal blooms.
Celebrating 20 Years of the UCSF Program for Breakthrough Biomedical Research
The program, supported by philanthropists Herb and Marion Sandler, funds ideas that challenge generally-accepted theories and have potentially transformative effects.
CRISPR Fingers Drug-Resistant Microbes in a ‘FLASH’
A research team led by scientists at UC San Francisco and the Chan Zuckerberg Biohub has developed a new CRISPR-based diagnostic tool, dubbed FLASH, that can rapidly identify any drug-resistant
Training Computers to Think More Like Scientists
Chuang and Keiser have shown how machine learning could lead scientists astray and how scientists might, in the future, avoid some of the pitfalls of training computers to be scientists.
Three Faculty Elected to American Academy of Arts and Sciences
UC San Francisco cancer biologist Alan Ashworth, PhD, structural biologist Yifan Cheng, PhD, and molecular physiologist Holly Ingraham, PhD, have been elected to the American Academy of Arts and
Talk on a Blood Test for Concussions Wins 2019 UCSF Grad Slam
Ten finalists competed in the fifth annual Grad Slam to inform and entertain with three-minute talks based on their own research.
‘Undruggable’ Parkinson’s Molecule Spills Its Secrets
UCSF researchers developed a strategy for targeting a key molecule implicated in Parkinson’s disease, opening up a potential new treatment strategy for the currently incurable movement disorder.
Two UCSF Graduate Students Named 2019 Weintraub Awardees
The awards, given by the Fred Hutchinson Cancer Research Center, recognize outstanding achievement in graduate studies in the biological sciences.
Not Just Neurons: Precision Signaling Architecture Discovered in Non-Neural Cells that Direct Development
UCSF lab found that a chemical that acts as a neurotransmitter in the nervous system is essential for cytonemes to mediate cell-to-cell communication between non-neural cells.
