University of California San Francisco
Give to UCSFRamani is featured for co-inventing sci-Plex, a new technique that enables high-throughput chemical screening using single-cell RNA-sequencing as a read-out.
After phages infect bacteria, they construct an impenetrable “safe room” inside of their host, which protects vulnerable phage DNA from antiviral enzymes. This compartment, which resembles a cell nucleus, is the most effective CRISPR shield ever discovered in viruses.
Research shows that after cells are subjected to certain stressful treatments, they appear to gain a new “superpower” that allows them to grow twice as fast as normal — a feature the authors call “supergrowth.”
Using standard animal model of Down syndrome, scientists were able to correct the learning and memory deficits associated with the condition with drugs that target the body’s response to cellular stresses.
In a breakthrough with important implications for the future of immunotherapy for breast cancer, UCSF scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
Now in its sixth year, the Best Global Universities rankings focus on schools’ academic research and reputation.
Research team has detected the immunological remnants of a common seasonal virus in spinal fluid from dozens of patients diagnosed with acute flaccid myelitis (AFM). The findings provide the clearest evidence to date that AFM is caused by an enterovirus (EV) that invades and impairs the central nervous system.
The UCSF scientists who identified the two known human genes that promote “natural short sleep” have now discovered a third, and it’s also the first gene that’s ever been shown to prevent the memory deficits that normally accompany sleep deprivation.
The NIH has awarded grants to Faranak Fattahi, Alexander Pollen, and Vasanth Vedantham to pursue highly innovative and unusually impactful biomedical research.
Julius received the prize “for discovering molecules, cells, and mechanisms underlying pain sensation.”
Researchers discovered a scorpion toxin that targets the “wasabi receptor,” which they think it can be used as a tool for studying chronic pain and inflammation, and may eventually lead to the development of new kinds of non-opioid pain relievers.