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How Cells Multitask: The Magic of Molecular Switches

Researchers at UCSF’s Quantitative Biosciences Institute (QBI) have observed how molecular switches regulate many different biological processes simultaneously. Their findings may shed light on how disease mutations operate, offering new ways to target malfunctioning switches and prevent illness.

David Julius Wins Nobel Prize for Work on Pain Sensation

David Julius, PhD, professor and chair of the Department of Physiology and Morris Herzstein Chair in Molecular Biology and Medicine at UC San Francisco, has won the 2021 Nobel Prize in Physiology or Medicine.

David Julius, PhD

Biography of David Julius

David Julius, PhD is professor and chair of the Department of Physiology at UC San Francisco and holds the Morris Herzstein Chair in Molecular Biology and Medicine.

David Julius and Sandy Johnson hugging after Breakthrough Prize win

Microbiome Medicine: Scientists Harness the Body’s ‘Bugs’ to Treat Asthma, MS and More

Plenty of probiotic yogurts, pickles and kombuchas claim to boost our digestive health with armies of microbes, but some scientists have more ambitious therapeutic plans for the “bugs” that colonize us. They hope to leverage these microbes as living therapeutics for a range of health conditions, including ulcerative colitis, multiple sclerosis, eczema and asthma. 

TED Talk: “Can We Create Vaccines that Mutate and Spread?”

The viruses that cause polio and COVID-19 mutate, but treatments for the diseases don’t. For over 20 years, UCSF and Gladstone Institutes scientist Leor Weinberger, PhD, has been thinking of ways to make vaccines work more efficiently by being adaptive, rather than static.

The Case of the Recurring Fever

An elderly man had symptoms no one could explain – until Amy Berger, MD, PhD, and her team investigated.

Comic-style illustration of a female doctor in the foreground, and three scientists in the background examining specimens with a microscope, test tube, and magnifying glass.