Novel Structure Found in Tumor Cells May Open Door to New Kinds of Cancer Therapies
UCSF researchers have figured out precisely what receptor tyrosine kinases are, how they form and their role in cancer.
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Smart Cell Therapies for Solid Cancers Ready to Move Toward Clinical Trials
Researchers at UCSF have demonstrated how to engineer smart immune cells that are effective against solid tumors, opening the door to treating a variety of cancers that have long been untouchable with immunotherapies.
New CRISPR Technology Offers Unrivaled Control of Epigenetic Inheritance
Scientists have figured out how to modify CRISPR’s basic architecture to extend its reach beyond the genome and into what’s known as the epigenome.
Pancreatic Cancer Cells Hijack Muscle Protein to Beef Up Their Metabolism
Cancer starts with mutations in a cell’s DNA, but new UCSF research shows that the endurance of a tumor relies on its ability to rapidly evolve and adapt to challenges brought about by the environment in which it grows.
Key Decision Point for Brain Development Identified
In a new study, UCSF and Stanford researchers have identified a central switch that appears to control when neural progenitor cells stop multiplying and start differentiating into mature neurons.
Store Fat or Burn It? Targeting a Single Protein Flips the Switch
UCSF researchers found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if all the mice eat a high-fat diet.
Probiotics: Health Hack or Hype?
We turned to UCSF scientists to better understand probiotics and the human microbiome they aim to influence.
Pandemic Brings an Unexpected Twist to Alum’s Protein Discovery
Susan Acton discovered ACE2 while searching for new cardiovascular drugs. Decades later, she was surprised to see it popping up in the news once COVID took hold.
Could this Llama-Inspired Nanobody Help Curtail COVID?
A UCSF team has engineered a tiny antibody capable of neutralizing the coronavirus.
UCSF and BridgeBio Pharma to Accelerate Therapies for Genetic Diseases
UCSF and BridgeBio Pharma, Inc. today announced a partnership to drive the advancement of academic innovations in genetically driven diseases into potential therapeutics for patients.
A Genetic Shortcut to Help Visualize Proteins at Work
A group at Gladstone Institutes and UCSF has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of protein complexes.
How Can We Be Sure the New COVID-19 Vaccines Are Safe?
We asked several UCSF experts for a personal take on what will convince them that a vaccine is safe.
Astonishing Animals That Illuminate Human Health
Giant lizards with superpowered hearts. Hairless rodents that don’t seem to age. Songbirds that babble like human babies. These and other scurrying, soaring, and slithering wonders are teaching scientists how our own bodies work – and how to fix them.
Drug Reverses Age-Related Mental Decline Within Days
In the new study, UCSF researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.
