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Non-Opioid Compounds Squelch Pain Without Sedation

A newly identified set of molecules alleviated pain in mice while avoiding the sedating affect that limits the use of opiates, according to a new study led by researchers at UC San Francisco.

Animated pills on a blue background

LSD-Like Molecules Counter Depression Without the Trip

Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that lasted up to two weeks.

3D computer model of the 5HT2a receptor