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Cancer's Next Magic Bullet May Be Magic Shotgun

A new approach to drug design, pioneered by a group of researchers at UCSF and Mt. Sinai, New York, promises to help identify future drugs to fight cancer and other diseases that will be more effective and have fewer side effects.

What Steers Vampires to Blood

Scientists have known for years that when vampire bats tear through an animal’s skin with their razor-sharp teeth, their noses guide them to the best spots – where a precise bite will strike a vein and spill forth nourishing blood. But nobody knew exactly how bats knew where to bite – until now.

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UCSF Team Describes Genetic Basis of Rare Human Diseases

Researchers at UCSF and in Michigan, North Carolina and Spain have discovered how genetic mutations cause a number of rare human diseases, which include Meckel syndrome, Joubert syndrome and several other disorders.

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Smarter Drug Delivery with Tejal Desai, PhD

<p>Swallowing pills means medication must face the challenge of surviving the harsh environment of the digestive tract. As a result, people must take larger doses than they need. Using micro and nano-fabrication techniques developed by the computer chip industry, Desai’s lab is creating tiny devices that take multiple drugs directly to where they are needed, using less medication, minimizing side effects and making the process safer for the patient.&nbsp;</p>

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Mining the Human Body with Michael Fischbach, PhD

<p>Having developed an algorithm that discovered a large quantity of drug-producing bacteria in and on humans, Fischbach has turned his lab’s attention to studying their populations and interactions with each other. This, he posits, can greatly influence a person’s overall health and disease.</p>

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UCSF Joins Caltech in Creative Problem Solving to Advance Health Care

<p>Experts at UCSF and Caltech are pushing the boundaries of creative problem solving to address important clinical problems with the hope that the talent pool at both institutions, combined with an entrepreneurial spirit, will advance health care innovation.</p>

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Men's and Women's Immune Systems Respond Differently to PTSD

Men and women had starkly different immune system responses to chronic post-traumatic stress disorder, with men showing no response and women showing a strong response, in two studies by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

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UCSF Team Shows How to Make Skinny Worms Fat and Fat Worms Skinny

Researchers exploring human metabolism at UCSF have uncovered a handful of chemical compounds that regulate fat storage in worms, offering a new tool for understanding obesity and finding future treatments for diseases associated with obesity.

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UCSF Team Views Genome As It Turns On and Off Inside Cells

UCSF researchers have developed a new approach to decoding the vast information embedded in an organism’s genome, while shedding light on exactly how cells interpret their genetic material to create RNA messages and launch new processes in the cell.

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