UCSF researchers have identified cells’ unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.
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The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and a UCSF research team now has discovered a reason why.
A new stem-cell discovery might one day lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts.
The promise of precision medicine could radically transform the existing health care model by collecting, integrating and analyzing comprehensive data across basic research and massive patient cohorts.
Scientists at the Gladstone Institutes and UCSF have made an important breakthrough: they have discovered a way to transform skin cells into mature, fully functioning liver cells that flourish.
Geneticists from Ohio, California and Japan used stem cells to correct a defective “ring chromosome” with a normal chromosome. Such therapy has the promise to correct chromosome abnormalities that give rise to birth defects, mental disabilities and growth limitations.
Researchers have developed a new way to study bone disorders and bone growth, using stem cells from patients afflicted with a rare, genetic bone disease.
In a finding that directly contradicts the standard biological model of animal cell communication, UCSF scientists have discovered that typical cells in animals have the ability to transmit and receive biological signals by making physical contact with each other, even at long distance.