Studying brain disorders is complicated for many reasons, not the least being the ethics of obtaining living neurons. To overcome that obstacle, UCSF postdoc Aditi Deshpande is starting with skin cells.
Research uses brain “organoids” — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of MDS, a rare genetic disorder that causes fatal brain malformations.
UCSF researchers are working to figure out how mouse stem cells divide and differentiate into acinar cells to rebuild the salivary gland after an injury. Such research could apply to patients who often lose the ability to produce saliva after undergoing radiation therapy for head and neck cancers.
The UCSF community is deeply saddened to learn of the passing of William K. Bowes Jr., a Bay Area venture capitalist whose dedicated volunteer service and generous philanthropy supported medical research, access to college, higher education and the arts.