Stem cell biologists at UCSF have demonstrated that IL-1 itself directly transforms the blood system by driving blood stem cells in the bone marrow to switch away from their restorative, rejuvenating role in blood renewal and towards emergency production of immune cells.
Strengthening the link between Zika virus and microcephaly, scientists at UCSF have discovered that a protein the virus uses to infect skin cells and cause a rash is present also in stem cells of the developing human brain and retina.
New research by UCSF stem cell biologists has revealed that a DNA-binding protein called Foxd3 acts like a genetic traffic signal, holding that ball of undifferentiated cells in a state of readiness for its great transformation in the third week of development.
UCSF scientists describe capturing and studying individual metastatic cells from human breast cancer tumors implanted into mice as the cells escaped into the blood stream and began to form tumors elsewhere in the body.
Zev Gartner is working to building a fully functioning 3-D human breast tissue that will allow him to test potential cancer therapies, an innovation that's earned him a spot among Popular Science's "Brilliant 10" this year.