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C. albicans opaque cells respond to a pheromone by schmooing, in preparation for
mating.
We do research on the
human pathogen C. albicans, (a type of yeast), which
changes its shape and other critical characteristics in response to
environmental conditions inside mammalian hosts.
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S. cerevisiae transcriptional mating type repressor proteins alpha2
and a1 bound to DNA. We do research
on the molecular mechanisms of how
cells know what mating type they are, how they switch internal states
to mate with partner cells, and how they change their internal circuitry in response to other external
conditions.
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