The University of California, San Francisco (UCSF) has three major, multi-building campuses in San Francisco. They are:
- Parnassus Heights – information and map
- Mission Bay – information and map
- Mount Zion – information and map
In addition, major programs and departments are located at 19 UCSF-owned or UCSF-leased sites throughout the city, and at UCSF affiliates San Francisco General Hospital and San Francisco Veterans Affairs Medical Center:
- 50 Beale Street
- Buchanan Dental Center, 100 Buchanan Street
- China Basin Building, 185 Berry Street
- 1635 Divisadero Street, adjacent to UCSF Mount Zion campus (see map)
- 250 Executive Park Boulevard
- 3360 Geary Boulevard

Laurel Heights Building, San Francisco
- 2300 Harrison Street
- Hunters Point Facility, 900 Palou Avenue
- Laurel Heights Building, 3333 California Street (see map)
- 2727 Mariposa Street
- 1930 Market Street
- 654 Minnesota Street
- 982 Mission Street
- Mission Center Building, 1855 Folsom Street
- 220 Montgomery Street
- Orthopaedic Institute, 1500 Owens Street, adjacent to UCSF Mission Bay campus (see map)
- 350 Parnassus Avenue, adjacent to UCSF Parnassus campus (see map)
- 2233 Post Street, adjacent to UCSF Mount Zion campus (see map)
- 2380 Sutter Street, adjacent to UCSF Mount Zion campus (see map)
- San Francisco General Hospital – information and map
- San Francisco Veterans Affairs Medical Center – information and map

