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Immunology Journal Club

Once a week throughout the academic year, two students and/or postdocs, or one faculty member presents a discussion of one or several related articles published in recent journals. Senior graduate students also have the opportunity to present their research-in-progress talks. All program members are strongly encouraged to attend and participate. It is one of the opportunities for program members to present in a large audience in the Immunology program. It also allows for discussion and exposure to current topics in the literature.

The journal clubs are held every Thursday at 9 - 10 a.m. in N-217 (unless otherwise indicated), Parnassus and are broadcast to Mission Bay, GH-S261. Please note changes in IM Events Email.

You may also download the videos at http://saa.ucsf.edu/irts/video/immuno_journal_club.htm


2007-2008 Journal Club Schedule
Fall Quarter • Winter Quarter • Spring Quarter

Download the updated 2007-08 Schedule

DATE SPEAKERS
9/20/07
Marine Champsaur
Graduate Student, Lanier Lab
"This summer everyone advises you to take your vitamin A
"
Ref: Peng G, Wang HY, Peng W, Kiniwa Y, Seo KH, Wang RF.
Tumor-Infiltrating gammadelta T Cells Suppress T and Dendritic Cell Function via Mechanisms Controlled by a Unique Toll-like Receptor Signaling Pathway.Immunity. 2007 Aug;27(2):334-48. Epub 2007 Jul 26. 

Katrina Hoyer
Postdoctoral Fellow, Abbas Lab
Ref: Janine L. Coombes, Karima R.R. Siddiqui, Carolina V. Arancibia-
Cárcamo, Jason Hall, Cheng-Ming Sun, Yasmine Belkaid, and Fiona Powrie. A functionally specialized population of mucosal CD103 DCs induces Foxp3 regulatory T cells via a TGF-beta- and retinoic acid-dependent mechanism.J Exp Med. 2007 Aug 6;204(8)
9/27/07 Cathleen Collins
Graduate Student, Brown Lab
"Hyper-IgE syndrome: STAT is where it's at""RBCs to the rescue: respiratory protein-generated reactive oxygen species as an antimicrobial strategy"
Ref: Jiang N, Tan NS , Ho B, Ding JL. Respiratory protein-generated reactive oxygen species as an antimicrobial strategy. Nat Immunol. 2007 Oct; 8(10):1114-22. Epub 2007 Aug 26.

Davina Wu
Graduate Student, Locksley Lab
Ref: Minegishi Y, Saito M, Tsuchiya S, Tsuge I, Takada H, Hara T, Kawamura N, Ariga T, Pasic S, Stojkovic O, Metlin A, Karasuyama H. Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature. 2007 Aug 30;448(7157):1058-62. Epub 2007 Aug 5.
10/4/07 Dr. Matija Peterlin
Professor in Residence
Department of Rheumatology

"AIRE and Aristoteles Socrates Onassis"

Ref: Giraud et al. An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus. Nature. 2007 Aug 23; 448(7156):934-7. Epub 2007 Aug 8.
10/11/07 Jesse Green
Graduate Student
"Fate Unsealed"
Ref. Cobaleda et al. "Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors." Nature. 2007 Sep 27;449(7161):473-7.

Andrew Gross
Postdoctoral Fellow
"LL37 + DNA + pDCs = Psoriasis?"
Lande et al. “Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide.” Nature Vol. 449, p564-69, doi:10.1038/nature06116
10/18/07

Julia Gilden
Gradute Student
"A Helping Hand for Naive Cells?"
Belz et al. “Minimal activation of memory CD8+T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+T cells.” Nature Immunology. 2007 Oct; 8(10): 1060.

Trung Pham
Postdoctoral Fellow
"Taking the road less conceivable."
Carman et al. "Transcellular Diapedesis Is Initiated by Invasive Posodomes.” Immunity. 2007 Jun; 26(6): 784-97.

10/25/07 N o Journal Club
11/1/07 Dr. Qizhi Tang
Assistant Adjunct Professor
Department of Surgery
"Taking Census of T Cells."
Ref: Moon JJ, Chu HH, Pepper M, McSorley SJ, Jameson SC , Kedl RM, Jenkins MK. Naive CD4(+) T Cell Frequency Varies for Diffrerent Epitopes and Predicts Repertoire Diversity and Response Magnitude. Immunity. 2007 Aug;27(2):203-13. Epub 2007 Aug 16.

11/8/07 Lisa Kelly
Graduate Student, Cyster Lab
"IgG4 and its Fab-ulous exchange: what is it good for?”
Bleeker et al. “Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange.” Science. 2007 Sep 14;317(5844):1554-7.

Michelle Toft
Graduate Student, Lowell Lab
Specific CpGs attenuate the effector response in arthritis
Wu et al. "Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk.” The Journal of experimental medicine. 2007 Aug 26; (204) 8: 1911-22.
11/15/07 Dr. Frances Brodsky
Professor, Depts. of Biopharmaceutical Sciences, Pharmaceutical Chemistry, Microbiology & Immunology
Andzelm et al (2007) Myosin IIA is required for cytolytic granule exocytosis in human NK cells. J. Exp. Med. 204: 2285-2291
Pinaki et al (2007) Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse. J. Exp. Med. 204: 2306-2320
11/22/07 Thanksgiving Holiday
11/29/07 Dr. Jason Cyster
Professor, Dept of Mirobiology & Immunology
Investigator, Howard Hughes Medical Institute
Morel et al (2007) Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature. Jun 28; 447:1116-20
12/6/07 Christina Penaranda
Graduate Student, Bluestone Lab
Lim et al. “Tumor Suppressor CYLD Regulates Acute Lung Injury in Lethal Streptococcus pneumoniae Infections.”
Immunity. 2007 August 27; 349–360

Armando Lemus
Graduate Student, Engel Lab
Bromberg et al. “The sphingosine 1-phosphate receptor 1 causes tissue retention by
inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics.”
Nature Immunology. 2007 November 25; 10.1038/ni1534
12/13/07 Dr. Jennifer Puck
Professor, Department of Pediatrics and Institute for Human Genetics
Kraft et al. Efficient Transplantation via antibody-based clearance of hematopoietic stem cell niches. Science. 2007 Nov; 318 (5854)1296-9
1/3/08 Jon Clingan
Graduate Student, Matloubian Lab
Joshi NS et al. “Inflammation directs memory precursor and short-lived effector CD8+ T cell fates via the graded expression of T-bet transcription factor”. Immunity. 27, 281-295

Lillian Seu
Postdoctoral Fellow
Anderson et al. “Promotion of Tissue Inflammation by the Immune Receptor Tim-3 Expressed on Innate Immune Cells.” Science. 2007 November 16; 1141-43/ni5853
1/10/08

Joyce Hu
Graduate Student, Matloubian Lab
Rothlin et al. “Tam receptors are pleiotropic inhibitors of the innate immune response.” Cell. 2007 December 14; 1124-36/ni5853

Linda Lee
Graduate Student, DeFranco Lab
Denning et al. “Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses”. Nature Immunology. 2007 Oct 8 (10), 1086-94

1/17/08 Dr. Philip Norris
Assistant Professor, Department of Pathology and Laboratory Medicine
1/24/08 Dr. Joanne Engel
Professor, Department of Medicine
1/31/08 Larry Shiow
Graduate Student, Cyster Lab

April Price

Graduate Student, Locksley Lab
Wakim et al. “Dendritic cell-induced memory T cell activation in nonlymphoid tissues.”
Science. 2008 Jan 11;319(5860):198-202.
2/7/08 Dr. Lewis Lanier
Professor, Departments of Microbiology & Immunology and the Cancer Research Center
2/14/08 Jonathan Esensten
Graduate Student
Kano et al. “The contribution of transcription factor IRF1 to the
interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17
differentiation of CD4+ T cells.” Nat Immunol. Jan 2008, 9(1):34-41.

Shuyi Zhang

Graduate Student, McKerrow Lab
Sanjuan MA et al. “Toll-like receptor signaling in macrophages links the autophagy pathway to phagocytosis.” Nature. Dec 2007, 450:1253-1257.
2/21/08 Dr. Lawrence Fong
Professor, Department of Medicine and Microbiology & Immunology
Adermann K et al. “Semen-derived amyloid fibrils drastically enhance HIV infection.” Cell. 2007 Dec 14;131(6):1044-6.
2/28/08 Emily Elliot
Graduate Student
D. Hartl et al. “Cleavage of CXCR1 on Neutrophils Disables Bacterial Killing in Cystic Fibrosis Lung Disease.” Nature Medicine. December 2007.

Corey Miller

Graduate Student
Mendez-Ferrer S et al. “Haematopoietic stem cell release is regulated by circadian oscillations.” Nature advance online publication. February 06, 2008.
3/6/08 Kristen Coakley
Graduate Student
Coornaert, B et al. “T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kB inhibitor A20.” Nature Immunology 9(3): p. 263-271. 2008

Michael Patnode

Graduate Student
Kagan, JC et al. “TRAM couples endocytosis of Toll-like receptor 4 to
the induction of interferon-beta.” Nature Immunology. 2008 Feb 24
3/13/08 Dr. William Seaman
Professor, Departments of Medicine, and Microbiology & Immunology
Chief, Medical Service, San Francisco VAMC

Kawai, T, et al. “HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression.” N Engl J Med. 358:353-61, 2008.

Scandling JD, et al. “Tolerance and Chimerism after Renal and Hematopoietic-Cell Transplantation.” N Engl J Med. 358:362-8, 2008.

Alexander SI, et al. “Chimerism and Tolerance in a Recipient of a Deceased-Donor Liver Transplant.” N Engl J Med. 358:369-74, 2008.
3/20/08 Alison Coady
Graduate Student, Sil Lab
Kanda, A et al. “Breast milk-mediated transfer of an antigen induces tolerance and
protection from allergic asthma.” Nature Immunology. 2008 Feb;14(2):170-5. Epub 2008 Jan 27.

Emily Thornton

Graduate Student
Crtam. “Regulation of a late phase of T cell polarity and effector functions.”
Cell. 2008 Mar 7;132(5):846-59.
3/27/08 Dr. Averil Ma
Rainin Distingushed Associate Professor, Department of Medicine

Kim et al. "It is UNC93B1 delivers nucleotide sensing toll-like receptors to endolysosomes," Nature 452;234 (2008).
4/3/08 Dr. Zena Werb
Professor and Vice Chair, Department of Anatomy

Movahedi et al. "Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T-cell suppressive activity." Blood. 2008 Feb 13; [Epub ahead of print]
4/10/08 No Journal Club
4/17/08 No Journal Club - Cancelled
4/24/08 Dr. Douglas Nixon
Professor, Department of Medicine/Experimental Medicine
5/1/08 Jennifer Giampaolo
Graduate Student

Jennifer Bando

Graduate Student
5/8/08 No Journal Club - Cancelled
5/15/08 Rebecca Botelho
Graduate Student, McCune Lab

Matt Wheeler
Graduate Student, DeFranco Lab
5/22/08 Dr. Richard Locksley
Professor, Departments of Medicine, and Microbiology & Immunology
Investigator, Howard Hughes Medical Institute
5/29/08 Dervla Issac
Graduate Student, Sil Lab

Brian Webster
Graduate Student
6/5/08 Joao Pereira
Postdoctoral Fellow

Serena Kwek

Postdoctoral Fellow

RT- Research Talk

View the 2005-06 Schedule
View the 2006-07 Schedule


© 2007 The Regents of the University of California. All rights reserved.