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Gladstone Scientists Regenerate Damaged Hearts By Transforming Scar Tissue into Beating Heart Muscle

April 18, 2012 Scientists at the UCSF-affiliated Gladstone Institutes announced a research breakthrough in mice that one day may help doctors restore hearts damaged by heart attacks — by converting scar-forming cardiac cells into beating heart muscle.

UCSF Stem Cell Studies to Focus on Muscular Dystrophy, Heart Disease, Cancer

May 06, 2011 Three UCSF scientists have received grants from the California Institute for Regenerative Medicine to advance their investigations of treatment strategies for degenerative muscle diseases, such as muscular dystrophy, and heart disease, and to determine why human embryonic stem cells are susceptible to forming tumors.

UCSF Stem Cell Building Opens, A Milestone for Pioneering Program

February 09, 2011 UCSF celebrates the opening of an architecturally unique stem cell building, a milestone in the history of UCSF’s pioneering stem cell research program, one of the largest and most comprehensive of its kind in the United States.

UCSF Receives Second Major Gift from Dolbys for Stem Cell Building

January 31, 2011 Ray and Dagmar Dolby this week donated $20 million to the University of California, San Francisco to provide funding for a stem cell building on the Parnassus campus.

Mother's Stem Cells Likely Key to Treating Genetic Disease Before Birth

January 18, 2011 UCSF researchers have tackled a decade-long scientific conundrum, and their discovery is expected to lead to significant advances in using stem cells to treat genetic diseases before birth.

UCSF team finds new source of immune cells during pregnancy

December 16, 2010 UCSF researchers have shown for the first time that the human fetal immune system arises from an entirely different source than the adult immune system, and is more likely to tolerate than fight foreign substances in its environment.

Cell of origin for brain tumors may predict response to therapy

December 14, 2010 For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer. A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma.

Hearing loss study reveals role of bone hardness in tissue function

November 17, 2010 Scientists are reporting the first direct evidence that a subtle change in the physical properties of a tissue can affect its function.

UCSF Stem-Cell Based Neurological, Liver Therapy Strategies Advanced

October 22, 2010 UCSF scientists have received two grants from the California Institute for Regenerative Medicine to refine their human embryonic stem cell-based strategies for treating neurological diseases and liver failure.

Justice Department Declines UC stem Cell Motion

September 24, 2010 The U.S. Department of Justice declined to consent to the University of California’s motion to intervene in Sherley v. Sebelius, the case regarding federal funding for human embryonic stem cell (hESC) research, on which UC had made a motion to the U.S. Federal Court of Appeals on Sept. 20.

UCSF's Kriegstein, UC File in Court on Stem Cell Injunction

September 20, 2010 The University of California filed a motion Sept. 20 with the U.S. Federal Court of Appeals to intervene in Sherley v. Sebelius, the case regarding whether federal funds could be used for human embryonic stem cell (hESC) research. UC is the nation’s first research institution to formally seek to intervene in the pending lawsuit.

Blood Stem Cell, Leukemia Link Illuminated in UCSF-Led Study

August 16, 2010 A UCSF-led team has discovered at least one key reason why blood stem cells are susceptible to developing the genetic mutations that can lead to adult leukemia.

UCSF-led team discovers familial link in rare childhood leukemia

August 09, 2010 A UCSF-led team has discovered a direct link between an inherited genetic mutation, a set of developmental abnormalities and a rare form of childhood leukemia called juvenile myelomonocytic leukemia, or JMML.

Human embryonic stem cells purified in new, rapid technique

August 05, 2010 UCSF researchers are reporting the first success in very rapidly purifying one type of embryonic stem cell from a mix of many different types of embryonic stem cells in the culture dish. The technique, which avoids the need to genetically alter the cells to distinguish them, is a key advance, the researchers say, for obtaining the appropriate cells for repairing specific damaged tissues.

Cocoa flavanols improve vascular and blood pressure measures for coronary artery disease patients

July 06, 2010 A new study by UCSF cardiologists and researchers found that high concentrations of cocoa flavanols decrease blood pressure, improve the health of blood vessels and increase the number of circulating angiogenic cells in patients with heart disease. The findings indicate that foods rich in flavanols – such as cocoa products, tea, wine, and various fruits and vegetables – have a cardio-protective benefit for heart disease patients.

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