Chair, Department of Biopharmaceutical Sciences
Kathleen
M. Giacomini, PhD
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- Professor
- Director,
Center for Pharmacogenomics
- Joint
appointments in School of Pharmacy, department of
pharmaceutical chemistry and School of Medicine,
department of cellular and molecular pharmacology
- PhD
degree, pharmaceutics, State University of New York
at Buffalo
- Research
specialty: pharmaceutical sciences, pharmacogenomics
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"What
a wonderful time to be a scientist. It was not that long
ago when classically trained scientists traditionally worked
in parallel with little interaction -- biologist, chemist,
geneticist, pharmaceutical scientist all moving ahead but
on individual tracks. While this isolationism was never
the norm at UCSF in particular, sea changes in science are
quickly making it history elsewhere. And the Human Genome
Project has been instrumental. It is becoming increasingly
clear that genetic variation is involved with drug response
and, along with it, the connection between the traditional
disciplines of pharmaceutical sciences and human genetics
is dissolving to be replaced by new collaborations of new
groupings of scientists all working toward the goal of applying
knowledge about genes and their proteins to ultimately ensure
the right and most effective medicines are tailored to the
special genetic needs of individuals with disease.
Here
faculty members in the department of biopharmaceutical sciences
are busy pioneering this new field of pharmacogenomics and
preparing PhD students, through a new graduate program,
to do the same. We are also busy uncovering new insights
about how drugs act in the body, how they are absorbed,
and how to best collect and organize information about genes
and other biological structures and processes using computers
and statistical methods."
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about Dr. Giacomini
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