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1st appeared 02 January 2001

Bishop and Debas to Lecture on Liver Cancer, Jan. 8

UCSF Chancellor J. Michael Bishop and School of Medicine Dean Haile T. Debas, will discuss the science and medicine of liver cancer on Monday, January 8, 3:30 to 5 p.m., in N 225.

The special lecture -- "Liver Cancer: Clinical Challenges and Mechanisms of Pathogenesis" -- is part of the Dean’s Research Seminar Series.

Hepatocellular carcinoma (HCC) is the eighth most common cancer in the world, with an estimated 350,000 new cases annually. Affected individuals survive an average of less than one year without a liver transplant. Possible factors in the pathogenesis include hepatitis B and C, chronic alcoholism, and dietary aflatoxin.

The monthly series of lectures has been sponsored by the School of Medicine's Dean’s Office for nearly 15 years. Bishop last spoke exactly three years ago -- in January 1998 -- before he became Chancellor. Although he sponsors the series, puts together each year’s roster of speakers, and personally attends nearly every lecture, Debas has never participated as a speaker.

"I am honored to be joining Mike Bishop to speak on this important topic," Debas said. Debas will summarize the clinical picture, including the results of hepatic resection, liver transplantation, and medical therapy, all of which show a dismal outcome and indicate a critical need for new approaches to treatment. Bishop will describe a mouse model that illuminates the genetic underpinnings of HCC and provides an improved setting for preclinical studies of potential new therapies.

The Dean’s Research Seminar Series was originated under Dean Rudi Schmid in the mid-1980s to provide a forum for School of Medicine faculty to share their work. The format is designed to emphasize the dynamic interface between basic science discoveries and the clinical applications that arise out of them.

The School of Medicine's Office of Communications is working to resolve technical difficulties in transmitting the lectures to SFGHMC, Mount Zion, and the SFVAMC. In the meantime, videotapes of many lectures from this and previous years are available. For more details, visit the School of Medicine website or contact Patti Meagher.


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