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1st appeared 28 September 2000

Cancer Scientist to Deliver First Edward Hill Lecture

Janet D. Rowley, MD, DScJanet D. Rowley, MD, DSc, who is internationally renowned for her studies of chromosome abnormalities in human leukemia and lymphoma, will present the first annual Edward C. Hill Endowed Lecture, Wednesday, October 3.

She will give her talk -- "Lessons From Leukemia " -- at 9 a.m., in HSW 300.

A physician and scientist, Rowley is the Blum-Riese Distinguished Service Professor of Medicine, Molecular Genetics and Cell Biology, and Human Genetics in the Pritzker School of Medicine, University of Chicago. She won the prestigious Lasker Award in 1998 for research that paved the way for identifying genetic alterations that cause cancer in humans and that allow for cancer diagnosis in patients at the molecular level.

The lectureship, sponsored by the UCSF department of obstetrics, gynecology and reproductive sciences, honors the outstanding and enduring work of Edward C. Hill, MD, UCSF professor emeritus of obstetrics, gynecology and reproductive sciences. The lectureship will bring an internationally renowned scholar to UCSF each year to address the University and community.

"This endowed lectureship is a fitting tribute to a distinguished clinician and teacher," said Eugene Washington, MD, MSc, chair and professor of the department of obstetrics, gynecology and reproductive sciences. "Dr. Hill has made significant contributions to women’s health through his excellence in medical care and excellence in training of generations of healthcare providers."

Hill, who will mark his 50th anniversary as a UCSF faculty member this year, was trained as an obstetrician-gynecologist, but spent most of his professional career focusing on care for women with cancer of the reproductive tract. As a close collaborator with George Papanicolaou, who developed the Pap smear, Hill played a major role in introducing this cervical cancer-screening test in the US and was one of the first physicians to push for the widespread use of the Pap smear. Hill remains an active teacher, still lecturing to residents and students and consulting in the department’s gynecologic oncology practice.

In addition to the Lasker Award -- often called "America's Nobel" because 59 of the recipients have subsequently won the Nobel Prize -- Rowley also has won the coveted Gairdner Award (1996) and the National Medal of Science (1998).

In 1972, using new techniques of chromosome identification, Rowley discovered the first consistent chromosome translocation in any human cancer, and during her career she has identified more than a dozen different recurring translocations. A translocation is a structural chromosome abnormality. These discoveries have revolutionized the view of hematologists, oncologists and cancer biologists regarding the critical importance of recurring chromosome abnormalities in leukemia and lymphoma. Also, by collaborating with hematologists, Rowley has shown that recurring chromosome abnormalities were the most important prognostic indicator of a patient’s likelihood of response to treatment and survival.

"We feel fortunate to have an individual of such distinction as Dr. Rowley and who so amply personifies Dr. Hill’s commitment to excellence as our inaugural lecturer," Washington said.

Links:

1998 Lasker Award to Janet Rowley (Univ.of Chicago)

Janet Rowley website

UCSF Dept. of Obstetrics, Gynecology and Reproductive Sciences


Source: Leslie Harris, News Services

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