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selected publications

Author Year Title Journal Vol Page No
Näthke, I.S., Heuser, J., Lupas, A., Stock, J., Turck, C.W. and Brodsky, F.M. 1992 Folding and trimerization of the clathrin triskelion hub. Cell 68 899-910
Liu, S-H., Wong, M.L., Craik, C.S. and Brodsky, F.M. 1995 Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs. Cell 83 257-267
Wilde, A., Beattie, E.C., Lem, L., Riethof, D.A., Liu, S-H., Mobley, W.C., Soriano, P. and Brodsky, F.M. 1999 EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 96 677-687
Ybe, J.A., Brodsky, F.M., Hofmann, K., Lin, K., Liu, S-H., Chen, L., Earnest, T.N., Fletterick, R.J. and Hwang, P.K. 1999 Clathrin self-assembly is mediated by a tandemly repeated superhelix. Nature 399 371-375
Liu, S-H., Towler, M.C., Chen, E., Chen, C-Y., Song, W., Apodaca, G. and Brodsky, F.M. 2001 A novel clathrin homologue that codistributes with cytoskeletal components functions in the trans-Golgi network. EMBO J. 20 272-284
Brodsky, F.M., Chen, C-Y., Knuehl, C., Towler, M.C., Wakeham, D.E. 2001 Biological basketweaving: clathrin-coated vesicle formation and function. Annu. Rev. Cell Dev. Biol. 17 517-568
Yang, D., Buchholz, F., Huang, Z., Goga, A., Chen, C-Y., Brodsky, F.M. and Bishop, J.M. 2002 Short RNA duplexes produced by hydrolysis with Escherichia coli Rnase III mediate effective RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 99 9942-9947
Stoddart, A., Dykstra, M.L., Brown, B.K., Song, W., Pierce, S.K. and Brodsky, F.M. 2002 Lipid rafts unite signaling cascades with clathrin to regulate BCR internalization. Immunity 17 467-472
Chen, C-Y., Reese, M.L., Hwang, P.K., Ota, N., Agard, D. and Brodsky, F.M. 2002 Clathrin light and heavy chain interface: a-helix binding superhelix via critical tryptophans. EMBO J. 21 6072-6082
Wakeham, D.E., Chen, C-Y., Greene, B., Hwang, P.K. and Brodsky, F.M. 2003 Clathrin self-assembly involves coordinated weak interactions favorable for cellular regulation. EMBO J. 22 4980-4990
Towler, M.C., Kaufman, S.J. and Brodsky, F.M. 2004 Membrane traffic in skeletal muscle. Traffic 5 129-139
Crotzer, V.L., Mabardy, A.S., Weiss, A. and Brodsky, F.M. 2004 T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization. J. Exp. Med. 199 981-991
Towler, M.C., Gleeson, P.A., Hoshino, S., Rahkila, P., Manalo, V., Ordahl, C. and Brodsky, F.M. 2004 Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has a role in myogenesis and muscle regeneration. Mol. Biol. Cell 15 3181-3195
Niiro, H., Allam, A., Stoddart, A., Brodsky, F.M., Marshall, A.J. and Clark, E.A. 2004 The B lymphocyte adaptor molecule of 32 kd regulates B cell antigen receptor internalization. J. Immunol. 173 5601-5609
Brodsky, F.M. 2004 Clathrin's Achilles' ankle.- News and Views. Nature 432 568-569
Wilbur, J., Hwang, P. and Brodsky, F.M. 2005 New faces of the familiar clathrin lattice. Traffic 6 346-350
Chen, C.-Y. and Brodsky, F.M. 2005 Hip1/Hip1R bind the conserved sequences of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivo. J. Biol. Chem. 280 6109-6117
Stoddart, A., Jackson, A.P. and Brodsky, F.M. 2005 Plasticity of B cell receptor internalization upon conditional depletion of clathrin. Mol. Biol. Cell 16 2339-2348
Wakeham, D.E., Abi-Rached, L., Towler, M.C., Wilbur, J.D., Parham, P. and Brodsky, F.M. 2005 Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution. Proc. Natl. Acad. Sci. USA 102 7209-7214
Chen, T.T., Li, L., Chung, D-H., Allen, C.D.C., Torti, S., Torti,F.M., Cyster, J.G., Chen, C-Y., Brodsky, F.M., Niemi, E.C., Nakamura, M.C., Seaman, W.E. and Daws, M.R. 2005 TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. J. Exp. Med. 202 955-965
Knuehl, C., Chen, C.-Y., Manalo, V., Hwang, P.K., Ota, N. and Brodsky, F.M. 2006 Novel binding sites on clathrin and adaptors regulate distinct aspects of coat assembly. Traffic 7 1581-1589