The UCSF Immunology Graduate Program is a component of both the Biomedical Sciences (BMS) program and the Program in Biological Sciences (PIBS). Currently, students interested in the program are admitted into the BMS program and elect to follow the Immunology Track at the end of the first year. First year BMS students pursue coursework with an emphasis on mammalian cells and tissues, including the immune system. Modern approaches for understanding the molecular mechanisms of cell, organ, and immune system function are studied as are integrative approaches toward defining the physiological in vivo importance of these mechanisms. We believe that this coursework will provide an excellent knowledge base for graduate students with a strong interest in immunology and related fields such as infectious disease. In addition, first year students do three research "rotations" in different BMS/Immunology laboratories to learn experimental approaches hands-on and to aid them in choosing a thesis laboratory and project. For students who elect the Immunology Track, the Immunology Graduate Program provides continuing advanced training in current developments of immunology and in other aspects of modern molecular and cellular biology via a weekly immunology student/faculty journal club, an annual immunology retreat, a yearly advanced topics seminar course, and a weekly seminar series by outstanding immunologists from around the U.S. and occasionally overseas.
In addition to the above courses and activities, our connection with PIBS provides our students, postdoctoral fellows and faculty with close interactions with scientists studying cell biology, genetics, biochemistry and molecular biology, developmental biology, biophysics, and neuroscience. As these fields are highly relevant to modern study of immunology, these connections enhance the education of students in the Immunology Program.
Participating Faculty
Abul Abbas, MBBS
Primary Research Interest: Immunology
T-cell regulation in tolerance and immunity
Nina Agabian, PhD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
Microbial Pathogenesis
Mark Anderson, MD, PhD
Primary Research Interest: Immunology
The Genetic Control of Autoimmune Disease
K. Mark Ansel, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Developmental and Stem Cell Biology
Regulation of gene expression in the immune system
Steinunn Baekkeskov, PhD
Primary Research Interest: Immunology
Molecular Mechanisms of Autoimmunity/Structure, Cell Biology, and Immunopathology of Autoantigens
Jody Baron, MD, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Innate and adaptive immunity to viral pathogens
Jeffrey Bluestone, PhD
Primary Research Interest: Immunology
Regulation of T-cell activation and tolerance during autoimmune and transplantation responses
Frances Brodsky, DPhil
Primary Research Interest: Immunology
Secondary Research Interest: Tissue/Organ Biology & Endocrinology
Intracellular Membrane Traffic: Mechanisms & Immune Function
George Caughey, MD
Primary Research Interest: Immunology
Secondary Research Interest: Tissue/Organ Biology & Endocrinology
Genetics, Structure and Function of Mast Cell Secretory Proteases
Harold Chapman, MD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Integrin signaling in lung fibrosis and cancer
Israel F. Charo, MD, PhD
Primary Research Interest: Immunology
Structure and Function of Chemokine Receptors
Lisa Coussens, PhD
Primary Research Interest: Cancer Biology & Cell Signaling
Secondary Research Interest: Immunology
Manipulating the Host Response to Cancer
Jeffery Cox, PhD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
Host-Pathogen Interactions Responsible for M. tuberculosis Virulence
Lindsey A. Criswell, MD, MPH
Primary Research Interest: Human Genetics
Secondary Research Interest: Immunology
Genetics and epidemiology of human autoimmune disease
Jason Cyster, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Molecular Regulation of Cell Migration and Survival in Lymphoid Tissues
Anthony DeFranco, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Regulation of B Lymphocyte and Macrophage Function by Cell Surface Receptors
Joanne Engel, MD, PhD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
Interaction of Bacterial Pathogens with their Host Eukaryotic Cells
David Erle, MD
Primary Research Interest: Immunology
Secondary Research Interest: Tissue/Organ Biology & Endocrinology
Immunopathogenesis of asthma; immune cell trafficking
Lawrence Fong, MD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Immunobiology of Dendritic Cells in Disease
Ed Goetzl, MD
Primary Research Interest: Immunology
Immunoregulatory G Protein-Coupled Receptors of T-Cells
Warner Greene, MD, PhD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
Molecular Analysis of HIV Pathogenesis
Carl Grunfeld, MD, PhD
Primary Research Interest: Vascular & Cardiac Biology
Secondary Research Interest: Immunology
Metabolic Changes and the Host Response to Infection
Hobart Harris, MD, MPH
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Lipoproteins and Immune Responses to Infection and Acute Injury
Nigel Killeen, D.Phil
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
The determination of T-cell fate
Matthew Krummel, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Molecular Coordination in Multipartite Interactions
Lewis Lanier, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Regulation of T cell and NK cell immune responses by activating and inhibitory receptors
Jay Levy, MD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
HIV Pathogenesis
Limin Liu, PhD
Primary Research Interest: Cancer Biology & Cell Signaling
Secondary Research Interest: Immunology
Metabolism and Regulation of Nitric Oxide Bioactivity
Richard Locksley, MD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Development of effector T lymphocytes
Clifford Lowell, MD, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Tyrosine Kinase Regulated Signal Transduction in Blood Cells
Averil Ma, MD, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Innate Immunity and Immunological Memory
Tippi C. MacKenzie, MD
Primary Research Interest: Immunology
Secondary Research Interest: Developmental & Stem Cell Biology
Tolerance induction after in utero stem cell transplantation or gene therapy
Jacquelyn Maher, PhD
Primary Research Interest: Tissue/Organ Biology & Endocrinology
Secondary Research Interest: Immunology
Pleiotropic effects of chemokines; Lipotoxicity
Mehrdad Matloubian, MD, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Lymphocyte Migration and Autoimmune Disease
Joseph McCune, MD, PhD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
Pathogenic Mechanisms and Treatment of HIV-1 Disease
James McKerrow, MD, PhD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
Biochemistry, Immunopathogenesis and Molecular Biology of Parasitic Diseases
Michael McManus, PhD
Primary Research Interest: Human Genetics
Secondary Research Interest: Developmental & Stem Cell Biology , Immunology
Mammalian microRNA and RNA Interference Pathways
Laura Napolitano, MD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
The Regulation of T Lymphopoiesis
Doug Nixon, MD, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Cellular immune responses to HIV
Scott Oakes, MD
Primary Research Interest: Cancer Biology & Cell Signaling
Secondary Research Interest: Immunology
Control of Intrinsic Pathways of Apoptosis by the BCL-2 Family of Proteins
Melanie Ott, MD, PhD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
Molecular Pathogenesis of HIV and Hepatitis C Virus Infections
Emmanuelle Passegué, PhD
Primary Research Interest: Developmental & Stem Cell Biology
Secondary Research Interest: Immunology
Molecular and cellular understanding of normal and leukemogenic hematopoiesis
B. Matija Peterlin, MD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Molecular biology of MHC II and HIV
Jennifer Puck, MD
Primary Research Interest: Immunology
Secondary Research Interest: Human Genetics
Inherited disorders of lymphocyte development
Jeroen Roose, PhD
Primary Research Interest: Cancer Biology and Cell Signaling
Secondary Research Interest: Immunology
Ras Signal Transduction in Lymphocytes and Cancer
Steve Rosen, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Roles of biological sulfation in leukocyte trafficking and tumorigenesis
Bill Seaman, MD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
The Role of Lymphocyte Subtypes in Immunity
Jeoung-Sook Shin, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Virology & Microbial Pathogenesis
Antigen presentation by dendritic cells and its role in the pathogenesis of asthma
Qizhi Tang, PhD
Primary Research Interest: Immunology
Regulatory T cell control of autoimmunity and transplant rejection
Eric Verdin, MD
Primary Research Interest: Virology & Microbial Pathogenesis
Secondary Research Interest: Immunology
HIV Pathogenesis and lymphocyte biology
Zena Vexler, PhD
Primary Research Interest: Neurobiology
Secondary Research Interest: Vascular & Cardiac Biology, Immunology
Inflammatory mechanisms of injury and repair after adult and neonatal stroke
Matthias Wabl, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Somatic Cell Genetics of the B Lymphocyte
Art Weiss, MD, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Cancer Biology & Cell Signaling
Signal Transduction Events and Lymphocyte Activation
David Wofsy, MD
Primary Research Interest: Immunology
Mechanisms of autoimmunity
Paul Wolters, MD
Primary Research Interest: Immunology
Secondary Research Interest: Tissue/Organ Biology & Endocrinology
Cellular and molecular pathogenesis of lung disease
Midori Yenari, MD
Primary Research Interest: Neurobiology
Secondary Research Interest: Vascular & Cardiac Biology, Immunology
Inflammatory mechanisms in cerebral ischemia
Scott Zamvil, MD, PhD
Primary Research Interest: Immunology
Secondary Research Interest: Neurobiology, Human Genetics
Novel Treatments for Multiple Sclerosis
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Biomedical Sciences (BMS) Graduate Program