Selected Publications

Original Articles
Cases, S., Smith, S.J., Zheng, Y.-W., Myers, H.M., Lear, S.R., Sande, E., Novak, S.,
Collins, C., Welch, C.B., Lusis, A.J., Erickson, S.K., and Farese, R.V., Jr. (1998)
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key
enzyme in triacylglycerol synthesis. Proc. Natl. Acad. Sci. USA 95:13018-13023.

Accad, M., Smith, S.J., Newland, D., Sanan, D., King, L.E., Jr., Linton, M.F., Fazio, S.,
and Farese, R.V., Jr. (2000) Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking ACAT1. J. Clin. Invest.
105:711–719.

Smith, S.J., Cases, S., Jensen, D.R., Sande, E., Tow, B., Sanan, D., Raber, J., Eckel,
R.H., and Farese, R.V., Jr. (2000) Obesity resistance and multiple mechanisms of
triglyceride synthesis in mice lacking DGAT. Nat. Genet. 25:87-90.

Buhman, K.K., Accad, M., Novak, S., Choi, R.S., Wong, J.S., Hamilton, R.L., and
Farese, R.V., Jr. (2000) Resistance to diet-induced hypercholesterolemia and
gallstone formation in ACAT2-deficient mice. Nat. Med. 6:1341–1347.

Chen, H.C., Smith, S.J., Ladha, Z., Jensen, D.R., Ferreira, L.D., Pulawa, L.K., McGuire,
J.G., Pitas, R.E., Eckel, R.H., and Farese, R.V., Jr. (2002) Increased insulin and leptin
sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1. J. Clin. Invest. 109:1049–1055.

Chen, H.C., Stone, S.J., Zhou, P., Buhman, K.K., and Farese, R.V., Jr. (2002)
Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl CoA:diacylglycerol acyltransferase 1 in white adipose tissue. Diabetes.
51:3189–3195.

Stone, S., Myers, H.M., Brown, B., Watkins, S., Feingold K., Elias P., and Farese, R.V.,
Jr. (2004) Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. J. Biol.
Chem. 279:11767–11776.

Stone S.J., Levin M., Farese R.V., Jr. (2006) Murine Acyl CoA:diacylglycerol
acyltransferase-2 (DGAT2): Membrane topology and identification of key functional
residues. J. Biol. Chem. 281:40273–40282.

Monetti, M., Levin, M., Watt, M.J., Sajan, M.P., Marmor, S., Hubbard, B.K., Stevens, R.D.,
Bain, J.R., Newgard, C.B., Farese, R.V., Sr., Hevener A., and Farese R.V., Jr. (2007)
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing
DGAT in the liver. Cell Metab. 6:69-78.

Guo, Y., Walther, T.C., Rao, M., Stuurman, N., Goshima, G., Terayama, K., Wong, J.S.
Vale, R.D., Walter, P., Farese, R.V., Jr. (2007) Functional genomic screen reveals
genes involved in lipid droplet formation and utilization. (Submitted)