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BMS 220 Basic and Clinical Aspects of Stem Cell Biology
Spring 2008, 3 units

This course provides an overview of stem cell biology that integrates a description of basic concepts and technologies. Emphasis is on using stem cells to treat common human diseases such as diabetes, neurodegenerative disorders, and cancer and practical limitations that must be overcome to achieve the goal of widespread therapeutic use.

Course Director: Susan Fisher
Teaching Assistant: Mark White
Course Duration: April 1 - June 5, 2008
Final Exam: take-home exam May 27-June 5
Times: 8:30-10:00 a.m., Tuesday/Thursday; Discussion Sections Fridays, 10:00 a.m.-12:00 noon
Location: Lectures - S-20 except May 1 in HSW-303 and June 5 in S-514; Discussions - S-18. All rooms are located on the Parnassus campus.

 

General Course and Instructor Evaluations
Download forms: General Evals and Instructor Evals

Due:   June 8 , 2008
*If you fill out the forms electronically, underline numerical ratings, highlights will not show up clearly when xeroxing.
*Keep the individual instructor's evaluations to one page per instructor - do not try to combine them.
*Return completed evaluations to Monique Piazza, electronically, or Box 0452 , HSE-1288, hard copy.

ANNOUNCEMENT! Tippi MacKenzie's lecture will take place on May 27, and Yerem Yeghiazarians's lecture will move to June 3.

Week Lecture# Date Day Time Room Topic Lecturer Downloads
1 1 1-Apr T 8:30-10 S-20 Early Human Embryonic Development Susan Fisher 
Lecture 1
Movies
Embryology Overview
Embryo Cleavage
Gastrulation
Implantation
Lateral Folding
Saggital Folding
2 3-Apr Th 8:30-10 S-20 hESC Derivation Susan Fisher 
Lecture 2

Movies
Movie 1
Movie 2
3 4-Apr F 10-12 S-18 Major Organ Systems: A Developmental Survey Susan Fisher, Michael McMaster Lecture 3
2 4 8-Apr T 8:30-10 S-20 Epigenetics and Reprogramming Robert Blelloch Lecture 4
No class (IRM retreat)
No discussion (IRM retreat)
3 5 15-Apr T 8:30-10 S-20 Gametogenesis Marco Conti Lecture 5
6 17-Apr Th 8:30-10 S-20 IVF Julie Lamb Lecture 6
Discussion 18-Apr F 10-12 S-18   Marco Conti Discussion 1
4 7 22-Apr T 8:30-10 S-20 Normal Hematopoiesis and Leukemic Transformation Emmanuelle Passegue Lecture 7
8 24-Apr Th 8:30-10 S-20 Therapeutic Applications of Hematopoietic Stem Cells Andy Leavitt Lecture 8
Discussion 25-Apr F 10-12 S-18

 

 Emmanuelle Passegue Discussion 2
5 9 29-Apr T 8:30-10 S-18 Cancer Stem Cells: Insights from Mouse Models Zena Werb 
Lecture 9
Reading List
10 1-May Th 8:30-10 HSW-303 Breast Cancer Stem Cells Thea Tlsty Lecture 10
Discussion 2-May F 10-12 S-18 Panel discussion Thea Tlsty Discussion 3
6 11 6-May T 8:30-10 S-20 Pancreatic Regeneration Mike German Lecture 11
12 8-May Th 8:30-10 S-20 Neuronal Stem Cells: Embryonic/Fetal Arnold Kriegstein Lecture 12
Discussion 9-May F 10-12 S-18   Anders Persson 
Discussion 4 
Supp Figures
7 13 13-May T 8:30-10 S-20 Neuronal Stem Cells: Adult Arturo Alvarez-Buylla Lecture 13
14 15-May Th 8:30-10 S-20 Glial Stem Cells David Rowitch Lecture 14:
part 1, part 2, part 3
Discussion 16-May F 10-12 S-18   TBA
8 15 20-May T 8:30-10 S-20 Cell-Based Therapies for Diabetes Peter Stock Lecture 15
16 22-May Th 8:30-10 S-20 Cardiac Development and Stem Cells Deepak Srivastava Lecture 16
Discussion 23-May F 10-12 S-18   Harold Bernstein Discussion 5
9 17 27-May T 8:30-10 S-20 The Human Fetus as the Target for Translation of Stem Cell Science
(distribution of take-home exam)		 Tippi MacKenzie Lecture 17
18 29-May Th 8:30-10 S-20 Liver Regeneration Holger Willenbring
Discussion 30-May F 10-12 S-18   Holger Willenbring Discussion 6
10 19 3-Jun T 8:30-10 S-20 Therapeutic Applications Yerem Yeghiazarians
  20 5-Jun Th 8:30-10 S-514 Collection of take-home exam  
updated: May 28, 2008
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